Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Irritable bowel syndrome__20002-both_sexes-1154 |
| Phenotype | NoPhenotypeAvailable |
| Upregulated in class | na_pos |
| GeneSet | CL21442, CANONICAL AND NON-CANONICAL NOTCH SIGNALING, AND FRINGE |
| Enrichment Score (ES) | 0.48632666 |
| Normalized Enrichment Score (NES) | 1.0141586 |
| Nominal p-value | 0.473 |
| FDR q-value | 0.85605764 |
| FWER p-Value | 1.0 |
| SYMBOL | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|
| 1 | NOTCH2 | 398 | 1.770 | 0.2087 | Yes |
| 2 | RFNG | 1703 | 0.998 | 0.2663 | Yes |
| 3 | HEY1 | 2210 | 0.861 | 0.3505 | Yes |
| 4 | JAG2 | 2281 | 0.846 | 0.4569 | Yes |
| 5 | MAML2 | 4017 | 0.555 | 0.4328 | Yes |
| 6 | HEYL | 4290 | 0.527 | 0.4863 | Yes |
| 7 | MFNG | 8080 | 0.259 | 0.3090 | No |
| 8 | LFNG | 8905 | 0.224 | 0.2923 | No |
| 9 | HEY2 | 9612 | 0.198 | 0.2788 | No |
| 10 | NRARP | 10286 | 0.175 | 0.2642 | No |
| 11 | DNER | 10613 | 0.165 | 0.2675 | No |
| 12 | DTX1 | 10806 | 0.159 | 0.2776 | No |
| 13 | JAG1 | 11271 | 0.147 | 0.2709 | No |
| 14 | NOTCH1 | 11568 | 0.139 | 0.2726 | No |
| 15 | RBPJ | 12881 | 0.107 | 0.2134 | No |
| 16 | MAML3 | 13745 | 0.090 | 0.1771 | No |
| 17 | HES5 | 14493 | 0.075 | 0.1453 | No |
| 18 | HES1 | 14791 | 0.070 | 0.1379 | No |
| 19 | DLL3 | 14887 | 0.068 | 0.1416 | No |
| 20 | MAML1 | 15324 | 0.062 | 0.1253 | No |
| 21 | NOTCH3 | 15468 | 0.059 | 0.1250 | No |
| 22 | DLL1 | 15599 | 0.056 | 0.1250 | No |
| 23 | NOTCH4 | 15652 | 0.055 | 0.1293 | No |
| 24 | DLL4 | 16935 | -0.000 | 0.0579 | No |
